Treating acute rheumatic fever

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Acute rheumatic fever.

Acute rheumatic fever is an inflammatory response to group A streptococcal infectionwhich typically occurs two to three weeks after a throat infection.Worldwide, approximately 500 000 new cases of acute rheumatic fever occur annually, and at least 15 million people have chronic rheumatic heart disease. 2 Acute rheumatic fever is characterised by a clinical syndrome, and the most common manifest...

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Immunologic Factors in Acute Rheumatic Fever Compared to Rheumatic Heart Disease

Background/Objective: To clarify the state of different immunologic factors in patients with acute rheumatic fever (ARF) and rheumatic heart disease (RHD) compared to healthy individuals.Patients and Methods: Patients with ARF (#21), patients with RHD six months after the onset of ARF (#19), and healthy children from the same age group with normal physical examination and no history of pharyngi...

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Acute Rheumatic Fever and Rheumatic Carditisin Izmir

Acute rheumatic fever is a non-suppurative complication of Streptococcus pyogenes which only licks the joints, however bites the heart valves, particularly the mitral, aortic or both, rarely the tricuspid valve, resulting in valvular endothelial ulceration, collagen degeneration, neovascularization, interstitial calcification and fibrosis associated with lymphocytic infiltration [1]. Currently ...

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Susceptibility to Acute Rheumatic Fever

Acute rheumatic fever is a major cause of heart disease in large parts of the world, but it remains unknown why only a small fraction of those who are infected with rheumatogenic group A streptococci develop an abnormal immune response that leads to acute rheumatic fever. An understanding of the mechanisms underlying host susceptibility can provide important insights into pathogenesis that in t...

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Incidence of acute rheumatic fever.

The incidence of acute rheumatic fever is decreasing rapidly in Malmo, Sweden. The findings of other investigators, which agree well with ours, indicate that this holds true for other parts of Scandinavia too. The frequency of rheumatic heart disease also seems to be rapidly decreasing. It is conceivable that the decrease in the incidence of rheumatic heart disease is even more pronounced than ...

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ژورنال

عنوان ژورنال: BMJ

سال: 2003

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.327.7416.631